Diazepam is N-demethylated by CYP3A4 and 2C19 to your Lively metabolite N-desmethyldiazepam, and is also hydroxylated by CYP3A4 to the active metabolite temazepam. N-desmethyldiazepam and temazepam are both equally further metabolized to oxazepam. Temazepam and oxazepam are mainly removed by glucuronidation.
常见：嗜睡、头晕、乏力，大剂量可有共济失调、震颤、顺行性遗忘、认知损害。
It is just a colorless to gentle yellow crystalline compound, insoluble in water. The molecular components is C16H13ClN2O as well as molecular body weight is 284.74. The structural components is as follows:
VALTOCO is the one prescription nasal spray utilized to instantly handle episodes of frequent seizures in Older people and youngsters six yrs and more mature. It’s distinctive from a everyday anti-seizure drugs—you employ VALTOCO only when essential.
ジアゼパムは、パーキンソン病の治療におけるレボドパの作用を阻害することがある。
If you think you've overdosed on diazepam, Get hold of your crisis solutions instantly or the nearest poison Management center. Overdoses of benzodiazepines (which includes diazepam) are usually manifested by indicators ranging from drowsiness, issue respiratory to coma.
Are allergic to diazepam. Have an eye trouble named acute narrow-angle glaucoma. What should really I explain to my health practitioner ahead of having VALTOCO?
A 2nd dose really should not be specified when there is worry about the individual’s respiration, they will need assist with their respiration, or have Severe drowsiness.
VALTOCO is really a prescription drugs useful for the shorter-expression remedy of seizure clusters (generally known as “episodes of frequent seizure activity” or “acute repetitive seizures”) in sufferers six a long time of age and more mature.
You are alarmed by how often the seizures come about, by how severe the seizure is, by how much time the seizure lasts, or by the color or respiration of the person.
VALTOCO might harm your unborn newborn. Are breastfeeding or want to breastfeed. VALTOCO passes into your breast milk and could harm your baby. Speak with your Health care service provider about The simplest way to feed your toddler if you utilize VALTOCO. Notify your Health care provider about many of the medicines you take, including prescription and in excess of-the-counter medicines, nutritional vitamins, and herbal health supplements.
“I used to be taking a gaggle of teenagers from the kids’s house to see a Motion picture. That weird emotion strike me inside the theater, so I obtained up for just check here a drink of water and the subsequent matter I understood I used to be on the ground acquiring my to start with grand mal seizure.
Persons suspected of staying depending on benzodiazepine medications are quite progressively tapered off the drug. Withdrawals may be life-threatening, especially when too much doses have been taken for prolonged durations.
“My neurologist and I under no circumstances regarded a right away-use seizure medication for me since my seizures haven't lasted much longer than three minutes, but I still felt like there was a lot more I could do. I decided I necessary to advocate for myself.